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Insect sting allergy undertreated in Europe - 15 million Europeans at risk

October 30, 2008

PDF Version

Supporting Materials:
press-release-venom-uk.pdf
A life-saving treatment for insect sting allergy is virtually unknown to the
majority of physicians in Europe, a new survey shows. 15 million people in the
EU are at risk of suffering severe allergic reactions if stung by bees or
wasps, but the disease is widely under-diagnosed and often inadequately treated 

The positive effect of allergy vaccination on bee and wasp venom allergy is
unknown to 60% of European physicians, according to a new survey performed by
ALK among 318 physicians from seven European countries. For children in
particular, 97% of patients treated with ALK's allergy vaccines are protected
if re-stung for up to 20 years after end of treatment*. According to the
survey, more than 70% of doctors do not know this. 

“Wasp and bee allergy is widely under-diagnosed and therefore often not
adequately treated. Patients should be referred to allergy specialists for
evaluation of their allergy, because most patients with a history of systemic
anaphylactic sting reaction develop systemic symptoms if stung again”, said Dr.
Beatrice Bilò, Senior physician at the Department of Internal Medicine at the
University Hospital of Ancona, Italy and chairman of the Insect Venom
Hypersensitivity Interest Group in the European Academy of Allergology and
Clinical Immunology. 

15 million EU-citizens at risk
Patients suffering from severe allergy to bee or wasp venom are constantly at
risk of experiencing potentially life-threatening allergic reactions if stung
by such insects. 

Epidemiological studies published in Current Opinion in Allergy and Clinical
Immunology in 2008 report a prevalence of self-reported systemic anaphylactic
reactions due to insect stings of around 3.5 % in some European countries.
Thus, up to 15 million people in the EU bear a risk of developing a severe
allergic reaction after being stung**. 

Such allergic reactions can be prevented by the use of venom immunotherapy with
ALK's subcutaneous allergy vaccines, resulting in dramatically improved quality
of life for the patients. Subcutaneous allergy vaccination is the only
available treatment that prevents allergic reactions due to insect stings. The
treatment is initiated in specialised clinics like that of Dr. Beatrice Bilò,
in which patients are offered a possibility of reaching the maintenance
protective dose in a few days or hours. Following this up-dosing phase,
patients receive regular maintenance injections for at least 3-5 years.	 

“Until the patient is protected against further severe reactions, patients
should receive emergency kits for self-administration including an epinephrine
auto-injector. In addition, we inform the patient about how to best avoid being
stung”, Dr. Bilò said. 
 

For further information, please contact: 
Jacob Frische, Director, ALK Group Communications, (+45) 22 24 75 51 

*Golden DB. et al. Outcomes of allergy to insect stings in children, with and
without venom immunotherapy. NEJM 2004. 351; 668-74. 

**Bilò BM. et al. Epidemiology of insect-venom anaphylaxis. Curr Opin Allergy
Clin Immunol 2008, 8:330-337.
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